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基本信息

洪海征副教授
办公地点:环境与生态学院大楼C428 / C419
Haizheng HongAssociated Professor
Office Location:C428 / C419 CEE Building
Tel:0592-2189879
Email:honghz@xmu.edu.cn

详细资料 - 洪海征副教授

个人履历 Brief CV

  • 美国施贵宝公司药代系研究员(2008-2011)

    厦门大学副教授(2011-)

    PhD, Environmental Toxicology, University of California at Riverside (2007)

    Research Investigator, Department of Biotransformation, Bristol-Myers Squibb Co. (2008-2011)

    Associate Professor, Xiamen University (2011-)

研究方向 Research Interests

  • 环境毒理学;环境组学;海洋持久性污染物毒理学

    Environmental toxicology, environmental omics, toxicology of marine POPs

代表性论文 Selected Publications

  • Hong, HZ; Li, DM; Shen, R; Wang, XH; Shi, DL. 2014. Mechanisms of Hexabromocyclododecanes Induced Developmental Toxicity in Marine Medaka (Oryzias melastigma) Embryos. Aquatic Toxicology, 152: 173-185

    Hong, HZ; Su, H; Ma, L; Yao, M; Iyer, RA; Humphreys, WG; Christopher, LJ. 2011. In vitro characterization of the metabolic pathways and cytochrome P450 inhibition and induction potential of BMS-690514, an ErbB/vascular endothelial growth factor receptor inhibitor. Drug Metabolism and Disposition, 39: 1658-1667

    Hong, HZ; Caceres-Cortes, J; Su, H; Huang, H; Roongta, V; Bonacorsi, SJ; Hong, Y; Tian, Y; Iyer, RA; Humphreys, GW; Christopher, J. 2011. Mechanistic studies on a P450-mediated rearrangement of BMS-690514: conversion of a pyrrolotriazine to a hydroxypyridotriazine. Chemical Research in Toxicology, 24: 125-134

    Hong, HZ; Su, H; Sun, H; Allentoff, A; Ekhato, IV; Theodore, C; Caceres-Cortes, J; Iyer, RA; Christopher, J. 2010. Metabolism and Disposition of [14C]BMS-690514 Following Oral Administration to Rats, Rabbits and Dogs. Drug Metabolism and Disposition, 38: 1189-1201

    Hong, HZ; Cao, HC; Wang, Y. 2007. In-vivo Detection and Genotoxicity of a Guanine-cytosine Intrastrand Crosslink Lesion. Nuclear Acids Research, 35(21): 7118-7127

部分科研课题 Selected Research Programmes

  • 2013年1月-2016年12月,国家自然科学基金青年科学基金项目“HBCD不同异构体对中国近海代表性桡足类的毒理研究”(41206090)

    2012年1月-2014年12月,教育部高等学校博士学科点专项科研基金“六溴环十二烷不同异构体在中国典型桡足类体内的代谢转化“(20120121120032)

荣誉奖励 Honors and rewards

  • 加州大学十校联盟毒理教学及科研项目 优秀研究生研究资助项目:LC-MS/MS analysis of DNA base damage induced by nanoparticles (2006-2008,负责人,$50000)

    加州大学河滨分校毒理年会最佳新生口头报告奖 (2004)