报告题目：Functions of the histone deacetylase HDA6 in development and transposon silencing in Arabidopsis

系列：“生态与环境讲坛”系列第217讲

报告人：吴克强 教授

时间：2018年10月11日（周四） 上午9:30-

地点：金泉楼A239

来访单位：台湾大学

邀请人：李庆顺 教授

摘要：Reversible histone acetylation and deacetylation at the N-terminus of histone tails play a crucial role in regulation of eukaryotic gene activity. Acetylation of core histones usually induces an “open” chromatin structure and is associated with gene activation, whereas deacetylation of histone is often correlated with “closed” chromatin and gene repression. Histone deacetylation is catalyzed by histone deacetylases (HDACs). A growing number of studies have demonstrated the importance of histone deacetylation/ acetylation in genome stability, transcriptional regulation and development in plants. Our recent studies indicate that HDACs interact with various chromatin remolding factors and transcription factors involved in transcriptional repression in multiple developmental processes and pathways in plants. In this talk, I will present our recent research on the function of HDACs in gene silencing and plant development.